Howdy doo readers!

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Sunday, November 21, 2010

Phosphate Trapping??

As I was perusing the Vibrant Life homepage from The Linus Pauling Institute, I came across their Nutrient Interactions section for Phosphorus and found this really cool study that has been reviewed by James P. Knochel, M.D. from the University of Texas Southwestern Medical School-Department of Internal Medicine.

Check it out...


"A recent study of 11 adult men found that a diet high in fructose (20% of total calories) resulted in increased urinary loss of phosphorus and a negative phosphorus balance (i.e., daily loss of phosphorus was higher than daily intake). This effect was more pronounced if the diet was also low in magnesium. A potential mechanism for this effect is the lack of feed back inhibition of the conversion of fructose to fructose-1-phosphate in the liver. In other words, increased accumulation of fructose-1-phosphate in the cell does not inhibit the enzyme that phosphorylates fructose, using up large amounts of phosphate. This phenomenon is known as "phosphate trapping". This finding is relevant because fructose consumption in the U.S. has been increasing rapidly since the introduction of high fructose corn syrup in 1970, while magnesium intake has decreased over the past century".

http://www.oralchelation.com/ingred/phosphorus.htm

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