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Sunday, November 21, 2010

How long does Phosphorus stay in the body?

Ever wonder how long it takes for a vitamin or mineral to metabolize in your body? Here's the summary from Hahn et.al's The Circulation of Phosphorus in Body Revealed By Application of Radioactive Phosphorus as Indicator:

The distribution of radioactive phosphorus administered to a rabbit was
investigated. It was found that within 27 days 45 % of the phosphorus given
was excreted through the kidneys and 11 5 % through the bowels. The average
time a phosphorus atom spends in the body was found to be 30 days. The ratio
between active and normal phosphorus was found to be highest in the kidney,
in the muscles and in the liver, and lowest in the bones, especially in the diaphysis.

It is probable that in the course of 27 days an equipartition of the active
phosphorus between the muscles and the blood takes place while about 9/10 of the
bone phosphate is protected against the influx of the active phosphorus. It could,
however, be shown by following up the ratio of the active phosphorus to normal
phosphorus in the urine that an exchange of the phosphorus atoms present in
the bones and in the blood, and thus an atomic rejuvenation of the bones to a
further extent, is still going on after the lapse of 21 days. Since the active phosphorus shows the same chemical behavior as normal phosphorus, the conclusions
arrived at apply to all the phosphorus taken up with the food.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1267135/pdf/biochemj01044-0021.pdf

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